CAAST-ACLH ACTIVITIES

1. Development of Globally Competetive Infrastructure

Procurement of high-end equipments to support advanced research, teaching and training in the identified areas.

Renovation of existing infrastructural facilities like challenge animal shed, and select laboratories.

2. Development of Globally Competetive Infrastructure

Procurement of high-end equipments to support advanced research, teaching and training in the identified areas

• Renovation of existing infrastructural facilities like challenge animal shed, and select laboratories

3. Knowledge Generation through Exposure to Advanced Areas in Livestock Health

(i) Improved vaccines
a. Thermostable vaccines for FMD
b. Thermostable vaccine for PPR
c. Combined vaccines for PPR+Sheeppox, PPR+Goatpox
(ii)New vaccines
a. DIVA-compatible negative marker vaccine for FMD
b. DIVA enabled Brucella vaccine for cattle/buffalo
(iii) New vaccine candidates
a. Marker vaccine for PPR
b. Recombinant PCV-2 protein as vaccine candidate
c. CSFV marker vaccine candidate using reverse genetics system
d. Recombinant Sheeppox+PPR vaccine candidate
(iv) Diagnostics
a. Companion diagnostics for FMD
b. DIVA compliant tests for PPR
c. ELISA for PCV-2 antibodies
d. Pen-side diagnostics for Brucella
e. Molecular/serological tests for haemo-parasitic infections in cattle/ buffalo
(v) Generation of induced pluripotent stem cells and its depository
(vi) Therapeutic intervention for treatment of disease conditions (Mastitis, diarrhea) caused by AMR
(vii) Immuno-nutrition approaches
a. Development of pre-/probiotics-based nutraceuticals and test their efficacy using nutritional, metabolic, immunological and nutrigenomics approaches
b. Feeding trials to validate potential of the proven nutraceuticals in improving the immune-competence of animals vaccinated against select bacterial and viral diseases
(viii) Genomic approaches
a. Generation of data on health and behavioural parameters in real time.
b. Study of immune-competency of animals and response to vaccination by SNP chips/ genotyping-by-sequencing (GBS)-based genome-wide association study (GWAS)

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